Biggest Questions in Science

At its essence, science pursues knowledge by asking and answering questions. In this collection, Scientific American Custom Media, along with our partners at The Kavli Prize, explore the work of scientists who pursue the biggest questions in neuroscience, nanoscience and astrophysics. From the atomic scale to the galactic, the truths these scientists have uncovered are fundamental, and they have reshaped our understanding of how the universe works.

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This special collection was produced for The Kavli Prize by Scientific American Custom Media, a division separate from the magazine's board of editors.

Image of the silhouette of a person looking up at a colorful, starry sky
Illustration of the brain with neon colors
January 1, 2019

Rewiring the Brain

Milky Way, illustration
August 25, 2022

Understanding the Inner Workings of Stars

A view of the starry night sky, with a person shining a flashlight at the stars
January 1, 2020

The Secrets of Award-Winning Science

Scientific skeletal and muscular image of the human body with red pain receptors present in the knee
January 1, 2020

Tracing the Neural Roots of Pain

The Earth against a blue background on the left, and the Earth twin against a red background on the right
December 12, 2024

Chasing Shadows, Finding Life: The Search for Earth’s Twin